In order to study the possibilities of applying tailings dissolved in acid mine drainage in the Jinchuan copper and nickel mine to the integrated treatment of mine tailings and acid mine drainage, the authors performedthe dissolution experiments in sulfuric acid. It is found that tailings dissolve quickly under the following constant parameters: higher than 3 mol/L sulfuricacid concentration, above 90℃ temperature, a appropriate liquid/solid, and strong agitation. The dissolution can produce amorphous silicon dioxide. The pre-roasting of samples in a laboratory Muffle furnace at 300℃ for 4 hours would be of benefit to the dissolution of chlorite, but not beneficial to the dissolution of tremolite. Olivine, serpentine and diopside can dissolve easily while the dissolution of tremolite and plagioclase is rather difficult. Such phenomena are related to the properties of the tailing minerals.