The Mujicun porphyry copper deposit is located in northern Taihang Mountains of North China Craton (NCC). The precise SHRIMP U-Pb dating and Hf isotope of diorite porphyry show that diorite porphyry formed at 142.0±1.5 Ma. The diorite porphyry has the εHf(t) value of -21.2~-17.9, corresponding to t^C_DM model ages of 2.3~2.5 Ga and having similar Hf isotopes to the gabbrodiorite with εHf(t) of -19.6~-15.3 in Wanganzhen complex. Re-Os isotopic dating technique for molybdenites collected from the porphyry type ores in the Mujicun porphyry Cu deposit was applied to confirm the age of mineralization. The Re-Os dating of five molybdenite samples from porphyry-type ore yielded Re-Os model ages ranging from 144.5 to 145.5 Ma, with an average of 144.8 ±1.4 Ma, and the isochron age is 145.3 ± 2.2 Ma, representing the metallogenic age of the Mujicun porphyry copper deposit. The interaction of crust-mantle materials is crucial to the formation of the Mujicun porphyry copper deposit. Mesozoic lithospheric extension might have induced the melting of the enriched lithospheric mantle in response to the asthenosphere uprising for generating these intermediate-acidic rocks in the region.