The removal of Pb2+from chrome yellow wastewater by hydroxylapatite adsorbent has been investigated with the batch method. The experimental result shows that, when 200~400 g/t hydroxylapatite adsorbent is used and the stirring time is longer than 60 minutes at normal temperature, the mass density of Pb2+in chrome yellow wastewater is reduced to lower than 0.5 mg/L, which comes up to the standard of industrial drain water(1.0 mg/L).