The Jiaodong gold ore district is one of the most important gold districts in China, and there are many lamprophyre veins in each gold deposit, which mainly spread parallel to gold ore veins. According to the intersections between the gold veins and the lamprophyre veins, the lamprophyres can be divided into three groups, belonging respectively to pre-mineralization period, mineralization period and post-mineralization period, This paper has made a detailed study on petrology, petochmistry, trace element geochemistry and oxygen, neodymium and stron- tium isotopic composition of lamprophyres from four typical gold deposits, namely Qixia,Rushan, Linglong and Jiaojia. The lamprophyres are characterized by high alkali, potassium and aluminium contents and high Mg#values, which are defined as Mg#=100 Mg/(Mg+Fe). The lamprophyres are sim-ilar to basaltic and basaltic_andesitic rocks in petrogenic character. The lamprophyres have high 87Sr/86Sr ratios, lowεNd(t) values, and theirδ18O values are between 6‰and 8‰, higher than those of generally-recognized mantle-derived rocks. There are good positive relationships 43 between Cr and Ni, K and Rb, and Sr and Ba respectively, and the ratios of these elements are close to those of rocks in the upper crust of the North China massif. All of these characteristics show that the source rocks of lamprophyres are related to the crust materials. The two-stage partial melting model of the Jiaodong Group can be used to explain the genetic mechanism of the lamprophyres.